{"id":5804,"date":"2021-12-30T02:02:26","date_gmt":"2021-12-29T17:02:26","guid":{"rendered":"https:\/\/fukuoka-endodontics.com\/?p=5804"},"modified":"2021-12-30T10:03:31","modified_gmt":"2021-12-30T01:03:31","slug":"regenerative-endodontics-aae%e3%81%ae%e3%82%ac%e3%82%a4%e3%83%89%e3%83%a9%e3%82%a4%e3%83%b3%e3%81%a8%e5%ae%9f%e9%9a%9b%e3%81%ae%e6%b2%bb%e7%99%82%e3%81%ae%e7%9b%b8%e9%81%95%e5%b0%8f%e5%85%90","status":"publish","type":"post","link":"https:\/\/fukuoka-endodontics.com\/?p=5804","title":{"rendered":"Regenerative Endodontics: AAE\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3068\u5b9f\u969b\u306e\u6cbb\u7642\u306e\u76f8\u9055\u2026\u5c0f\u5150\u306e\u6cbb\u7642\u301c#9 Regeneration 2\u56de\u76ee\u7d42\u4e86\u21e8\u7d4c\u904e\u89b3\u5bdf\u3078\u79fb\u884c"},"content":{"rendered":"

7\u6b73\u306e\u5973\u5150\u3002<\/p>\n

\u30bb\u30df\u30ca\u30fc\u306b\u51fa\u3066\u3044\u308b\u5148\u751f\u304b\u3089\u306e\u7d39\u4ecb\u3067\u770c\u5916\u304b\u3089\u6765\u9662\u3055\u308c\u305f\u3002<\/p>\n

\u4e3b\u8a34\u306f\u524d\u6b6f\u90e8\u306e\u4e3b\u5f35\u3068\u5931\u6d3b\u306b\u3068\u3082\u306a\u3046\u6839\u306e\u672a\u9589\u9396\uff08\u7d39\u4ecb\u3055\u308c\u305f\u6b6f\u79d1\u533b\u5e2b\u306e\u4e3b\u8a34\u304b\u3082\u3057\u308c\u306a\u3044\u3002\uff09<\/p>\n

\u6b6f\u5185\u7642\u6cd5\u5b66\u7684\u691c\u67fb\u3092\u304a\u3053\u306a\u3063\u305f\u3002<\/p>\n

#8 Cold+1\/3, Perc.(-), Palp.(-), BT(-), Perio Probe(WNL), Mobility(WNL)<\/p>\n

#9 Cold N\/A, Perc.(-), Palp.(+), BT(-), Perio Probe(WNL), Mobility(WNL), Sinus tract(+)<\/p>\n

#10 Cold+2\/2, Perc.(-), Palp.(-), BT(-), Perio Probe(WNL), Mobility(WNL)<\/p>\n

PA\u306f\u4ee5\u4e0b\u306b\u306a\u308b\u3002<\/p>\n

\"\"<\/p>\n

\"\"<\/p>\n

\u6b6f\u6839\u306e\u9577\u3055\u306f\u5de6\u53f3\u5bfe\u79f0\u3067\u3042\u308b\u3053\u3068\u304b\u3089\u3001\u6b6f\u6839\u304c\u592a\u304f\u306a\u308b\u524d\u306b\u6b6f\u9ac4\u304c\u5931\u6d3b\u3057\u3066\u3057\u307e\u3063\u305f\u306e\u3060\u308d\u3046\u3068\u3044\u3046\u3053\u3068\u304c\u4e88\u60f3\u3067\u304d\u308b\u3002<\/p>\n

\u307e\u305f\u3001CBCT\u3082\u64ae\u5f71\u3057\u305f\u3002<\/p>\n

\"\"<\/p>\n

\u4ee5\u4e0a\u304b\u3089\u6b6f\u5185\u7642\u6cd5\u5b66\u7684\u75c5\u540d\u306f\u4ee5\u4e0b\u306b\u306a\u308b\u3002<\/p>\n

Pulp Dx: Pulp Necrosis<\/p>\n

Periapical Dx: Chronic apical abscess<\/p>\n

Recommended Tx: Regenerative Endodontics<\/p>\n

Regenerative Endodontics\u306b\u3064\u3044\u3066\u3054\u4e21\u89aa\u306b\u8aac\u660e\u3057\u305f\u3002<\/p>\n

AAE\u306e\u6cbb\u7642\u306b\u95a2\u3059\u308bInformed Consent \u3092\u53c2\u8003\u306b\u3057\u3066\u3044\u308b\u3002<\/strong><\/span><\/h1>\n

AAE Clinical Considerations for a Regenerative Procedure Revised<\/strong><\/span><\/a><\/h1>\n

2021.5.18\u306b\u6539\u8a02\u3055\u308c\u3066\u3044\u308b\u3002<\/p>\n

\"\"<\/p>\n

\"\"<\/p>\n

\u6539\u8a02\u306f\u5b9a\u671f\u7684\u306b\u3055\u308c\u3066\u3044\u308b\u304c\u3001\u307b\u3068\u3093\u3069\u5909\u66f4\u306f\u306a\u3044\u3002<\/p>\n

\u305d\u3057\u3066\u5404\u7a2e\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u4f4e\u3059\u304e\u308b\u3002<\/p>\n

\u4e3b\u306a\u8981\u70b9\u306f\u4ee5\u4e0b\u306b\u306a\u308b\u3002<\/p>\n

These considerations should be seen as one possible source of information and, given the rapid evolving nature of this field, clinicians should also actively review new findings elsewhere as they become available.<\/p>\n

\u5e8f\u6587\u306b\u8a18\u3055\u308c\u3066\u3044\u308b\u8a00\u8449\u306f\u3053\u306e\u30ac\u30a4\u30c9\u3092\u53c2\u8003\u306b\u6cbb\u7642\u3057\u306a\u3055\u3044\u3068\u66f8\u3044\u3066\u3042\u308b\u304c\u3001\u65b0\u3057\u3044\u767a\u898b\u304c\u51fa\u3066\u304f\u308c\u3070\u305d\u308c\u306f\u4f55\u3067\u3082review\u3057\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u3068\u66f8\u3044\u3066\u3042\u308b\u3002<\/p>\n

\u3044\u3064\u307e\u3067\u3082\u904e\u53bb\u306e\u907a\u7269\u306b\u62d8\u308b\u65e5\u672c\u3068\u30a2\u30e1\u30ea\u30ab\u306e\u6b6f\u79d1\u533b\u7642\u306e\u5927\u304d\u306a\u9055\u3044\u304c\u3001\u3053\u3053\u3067\u3042\u308b\u3002<\/strong><\/span><\/h1>\n

\u3055\u3089\u306b\u8aad\u307f\u9032\u3081\u3066\u3044\u304f\u3002<\/p>\n

Case Selection:<\/strong><\/span><\/h1>\n

\u2022 Tooth with necrotic pulp and an immature apex.(\u6b6f\u9ac4\u58ca\u6b7b\u3057\u305f\u6839\u672a\u5b8c\u6210\u6b6f)
\n\u2022 Pulp space not needed for post\/core, final restoration.(\u30dd\u30b9\u30c8\u3084\u30b3\u30a2\u3084\u6700\u7d42\u88dc\u7db4\u304c\u4e0d\u8981\u306a\u75c7\u4f8b\uff09
\n\u2022 Compliant patient\/parent.\uff08\u5354\u529b\u6027\u304c\u3042\u308b\u60a3\u8005\u3055\u3093\uff09
\n\u2022 Patients not allergic to medicaments and antibiotics necessary to complete procedure,\u00a0ASA 1 or 2.\uff08ASA1\u304b2\u306e\u5065\u5eb7\u306a\u60a3\u8005\u3055\u3093\uff09<\/p>\n

Informed Consent<\/strong><\/span><\/h1>\n

\u2022 Two (or more) appointments.\uff082\u56de\u4ee5\u4e0a\u306e\u30a2\u30dd\u30a4\u30f3\u30c8\u304c\u5fc5\u8981\u306a\u53ef\u80fd\u6027\uff09
\n\u2022 Use of antimicrobial(s).\uff08\u6297\u751f\u7269\u8cea\u3092\u4f7f\u7528\u3059\u308b\u3053\u3068\u304c\u3042\u308b\u30023Mix\u306e\u3053\u3068\u3067\u3042\u308b\u3002\uff09
\n\u2022 Possible adverse effects: staining of crown\/root, lack of response to treatment,\u00a0pain\/infection.\uff08\u6b6f\u7259\u306e\u5909\u8272\u3001\u6cbb\u7642\u3001\u75db\u307f\u30fb\u611f\u67d3\u306b\u5bfe\u3057\u3066\u53cd\u5fdc\u3057\u306a\u3044\u53ef\u80fd\u6027\uff09
\n\u2022 Alternatives: MTA apexification, no treatment, extraction (when deemed\u00a0non salvageable).(\u4ee3\u66ff\u6cbb\u7642\uff1aMTA\u30a2\u30da\u30ad\u30b7\u30d5\u30a3\u30b1\u30fc\u30b7\u30e7\u30f3, \u6cbb\u7642\u3057\u306a\u3044, \u629c\u6b6f\uff09<\/p>\n

First Appointment<\/span><\/strong><\/h1>\n

\u2022 Local anesthesia, dental dam isolation and access.\uff08\u9ebb\u9154\u3001\u30e9\u30d0\u30fc\u30c0\u30e0\u3001\u30a2\u30af\u30bb\u30b9\u30d7\u30ec\u30d1\u30ec\u30fc\u30b7\u30e7\u30f3\u5fc5\u8981\uff09<\/p>\n

\u2022 Copious, gentle irrigation with 20ml NaOCl using an irrigation system that minimizes the\u00a0possibility of extrusion of irrigants into the periapical space (e.g., needle with closed end and side-vents, or EndoVac). Lower concentrations of NaOCl are advised [1.5%-3% NaOCl (20mL\/canal, 5 min) and then irrigated with saline or EDTA (20 mL\/canal, 5 min), with irrigating needle positioned about 1 mm from root end, to minimize cytotoxicity to stem cells in the apical tissues.\uff0820ml\u306e1.5~3%\u306e\u30d2\u30dd\u30af\u30ed<\/strong><\/span>\u3067\u6d17\u6d44\u3002Closed\u306e\u30cb\u30fc\u30c9\u30eb\u304c\u671b\u307e\u3057\u3044\u3002<\/span><\/strong>\u307e\u305f\u306fEndoVac\u4f7f\u7528\u3002\u305d\u306e\u5f8c\u300120ml\u306eEDTA\u3067\u6839\u7ba1\u3092\u6d17\u6d44\u3059\u308b\uff09<\/p>\n

\u2022 Dry canals with paper points.\uff08\u30da\u30fc\u30d1\u30fc\u30dd\u30a4\u30f3\u30c8\u3067\u6839\u7ba1\u3092\u4e7e\u71e5\uff09<\/p>\n

\u2022 Place calcium hydroxide or low concentration of triple antibiotic paste. \uff08\u6c34\u9178\u5316\u30ab\u30eb\u30b7\u30a6\u30e0\u304b3Mix\u3092\u6839\u7ba1\u306b\u8cbc\u85ac\uff09<\/p>\n

\u2022 Seal with 3-4mm of a temporary restorative material such as CavitTM, IRMTM, glass-ionomer or another temporary material. Dismiss patient for 1-4 weeks.(Caviton\u7b49\u3067\u4eee\u5c01\u3057\u30011~4\u9031\u9593\u5f8c\u306b\u7d4c\u904e\u89b3\u5bdf\u3059\u308b\uff09<\/p>\n

Second Appointment (1-4 weeks after 1st visit)<\/span><\/strong><\/h1>\n

\u2022 Assess response to initial treatment. If there are signs\/symptoms of persistent infection, consider additional treatment time with antimicrobial, or alternative antimicrobial.\uff081\u56de\u76ee\u306e\u6cbb\u7642\u306e\u8a55\u4fa1\u3092\u3059\u308b\u3002\u3082\u3057\u554f\u984c\u304c\u3042\u308c\u3070\u518d\u5ea6\u6d17\u6d44\u3092\u884c\u3046\u304b\u3053\u306e\u6cbb\u7642\u81ea\u4f53\u3092\u6b62\u3081\u308b\u304b\u3069\u3061\u3089\u304b\u3002\uff09<\/p>\n

\u2022 Anesthesia with 3% mepivacaine without vasoconstrictor<\/strong><\/span>, dental dam isolation.\uff083%\u30e1\u30d4\u30d0\u30ab\u30a4\u30f3\uff1d3%\u30b9\u30ad\u30e3\u30f3\u30c9\u30cd\u30b9\u30c8\u3092\u4f7f\u7528<\/strong><\/span>\uff09<\/p>\n

\u2022 Copious, gentle irrigation with 20ml of 17% EDTA.(20ml\u306eEDTA\u3067\u6d17\u6d44\uff09<\/p>\n

\u2022 Dry with paper points.\uff08\u30da\u30fc\u30d1\u30fc\u30dd\u30a4\u30f3\u30c8\u3067\u6839\u7ba1\u4e7e\u71e5\uff09<\/p>\n

\u2022 Create bleeding into canal system by over-instrumenting (endo file, endo explorer)\u3000(induce by rotating a pre-curved K-file at 2 mm past the apical foramen with the goal of having the entire canal filled with blood to the level of the cemento\u2013enamel junction). An alternative to creating of a blood clot is the use of platelet-rich plasma (PRP), platelet rich fibrin (PRF) or autologous fibrin matrix (AFM).\uff08\u30aa\u30fc\u30d0\u30fc\u5f62\u6210\u3057\u3066\u6839\u7ba1\u5185\u306b\u8840\u6db2\u3092\u9001\u308b\uff09<\/p>\n

\u2022 Stop bleeding at a level that allows for 3-4 mm of restorative material.\uff08\u4fee\u5fa9\u90e8\u4f4d\u306e3~4mm\u76f4\u4e0b\u3067\u6b62\u8840\u3055\u305b\u308b\uff09<\/p>\n

\u2022 Place a resorbable matrix such as CollaPlug, Collacote, CollaTape over the\u00a0blood clot if necessary and white MTA as capping material.\uff08\u30b3\u30e9\u30d7\u30e9\u30b0\u3001\u30b3\u30e9\u30c6\u30fc\u30d7\u3001\u30b3\u30e9\u30b3\u30fc\u30c8\u306a\u3069\u306e\u6750\u6599\u3092\u51fa\u8840\u306e\u4e0a\u306b\u7f6e\u304f\uff09<\/p>\n

\u2022 A 3\u20134 mm layer of glass ionomer (e.g. Fuji IXTM, GC America, Alsip, IL) is\u00a0flowed gently over the capping material and light-cured for 40 s. MTA has been associated with discoloration. Alternatives to MTA (such as bioceramics or tricalcium silicate cements [e.g., Biodentine\u00ae, Septodont, Lancasted, PA, USA, EndoSequence\u00ae BC RRM-Fast Set Putty, Brasseler, USA]) should be considered in teeth where there is an esthetic concern.(MTA\u306e\u4e0a\u306b\u4fee\u5fa9\u6750\u6599\u3092\u7f6e\u304f\u3002\u5909\u8272\u304c\u6c17\u306b\u306a\u308c\u3070\u3001Biodentine\u3084BC putty\u3092\u7528\u3044\u308b\u3002\uff09<\/p>\n

\u2022 Anterior and Premolar teeth – Consider use of Collatape\/Collaplug and restoring with 3mm of a nonstaining restorative material followed by bonding a filled composite to the beveled enamel margin.\uff08\u524d\u6b6f\u2192\u6700\u7d42\u7684\u306b\u306fCR\u3067\u5145\u586b\uff09<\/p>\n

\u2022 Molar teeth or teeth with PFM crown – Consider use of Collatape\/Collaplug and restoring with 3mm of MTA, followed by RMGI, composite or alloy.\uff08\u81fc\u6b6f\u2192CR\u304b\u91d1\u5c5e\u4fee\u5fa9\u3078\uff09<\/p>\n

Follow-up (6-, 12-, 24-months)<\/strong><\/span><\/h1>\n

\u2022 Clinical and Radiographic exam\uff08\u81e8\u5e8a\u691c\u67fb\u30fb\u30ec\u30f3\u30c8\u30b2\u30f3\u691c\u67fb\u5fc5\u8981\uff09<\/strong><\/span><\/p>\n

\u2460No pain, soft tissue swelling or sinus tract (often observed between first and\u00a0second appointments).\uff08\u75db\u307f\u3084\u8edf\u7d44\u7e54\u306e\u816b\u8139\u304c\u306a\u3044\u3042\u308b\u3044\u306fSinus tract\u304c\u6d88\u5931\u3002\u3053\u308c\u306f\u3057\u3070\u3057\u30701\u56de\u76ee\u30682\u56de\u76ee\u306e\u6cbb\u7642\u306e\u9593\u306b\u8d77\u304d\u308b\u3053\u3068\u304c\u591a\u3044\uff09
\n\u2461Resolution of apical radiolucency (often observed 6-12 months after treatment) \uff08\u6839\u5c16\u75c5\u5909\u306e\u55aa\u5931\u3002\u3057\u3070\u3057\u3070\u6cbb\u7642\u5f8c6~12\u30f6\u6708\u3067\u751f\u3058\u308b\u3053\u3068\u304c\u591a\u3044\uff09
\n\u2462Increased width of root walls (this is generally observed before apparent increase\u00a0in root length and often occurs 12-24 months after treatment).
\n\uff08\u6839\u7ba1\u9577\u3068\u6839\u7ba1\u58c1\u306e\u5897\u5927. \u6cbb\u7642\u5f8c12~24\u30f6\u6708\u3067\u8d77\u304d\u308b\u3053\u3068\u304c\u591a\u3044\uff09
\n\u2463Increased root length.\uff08\u6b6f\u6839\u306e\u6210\u9577\uff09
\n\u2464Positive Pulp vitality test response\uff08Cold test\u7b49\u306b\u5bfe\u3059\u308b\u967d\u6027\u53cd\u5fdc\uff09<\/strong><\/span>
\n\u2465Recommended yearly follow-up after the first 2 years\uff08\u8853\u5f8c2\u5e74\u306e\u6700\u4f4e\u9650\u306e\u7d4c\u904e\u89b3\u5bdf\uff09
\n\u2466CBCT is highly recommended for initial evaluation and follow-up visits\uff08CBCT\u306e\u64ae\u5f71\uff09<\/p>\n

\u2022 The degree of success of Regenerative Endodontic Procedures is largely measured by the extent to which it is possible to attain primary, secondary, and tertiary goals:<\/span><\/strong><\/p>\n

\u2460Primary goal: The elimination of symptoms and the evidence of bony healing.\uff08\u7b2c1\u306e\u30b4\u30fc\u30eb\uff1a\u75c7\u72b6\u306e\u55aa\u5931\u3068\u6839\u5c16\u75c5\u5909\u306e\u6cbb\u7652\uff09<\/p>\n

\u2461Secondary goal: Increased root wall thickness and\/or increased root length(desirable, but perhaps not essential)\uff08\u7b2c2\u306e\u30b4\u30fc\u30eb\uff1a\u6839\u7ba1\u58c1\u30fb\u6b6f\u6839\u306e\u6210\u9577\u3002\u7406\u60f3\u7684\u3060\u304c\u30de\u30b9\u30c8\u3067\u306f\u306a\u3044\uff09<\/p>\n

\u2462Tertiary goal: Positive response to vitality testing (which if achieved, could\u00a0indicate a more organized vital pulp tissue)\uff08\u7b2c3\u306e\u30b4\u30fc\u30eb\uff1a\u751f\u6d3b\u53cd\u5fdc\u306e\u7372\u5f97<\/strong><\/span>\uff09<\/p>\n

\n

\u4ee5\u4e0a\u304cAAE\u306eRegeneration\u306b\u5bfe\u3059\u308b\u6307\u91dd\u3067\u3042\u308b\u3002<\/p>\n

\u79c1\u304c\u77e5\u308b\u9650\u308a\u3001<\/p>\n

\u9055\u548c\u611f\u304c\u3042\u308b\u306e\u304c\u9752\u5730\u3067\u8a18\u3057\u305f\u90e8\u5206<\/strong><\/span><\/h1>\n

\u3067\u3042\u308b\u3002<\/p>\n

\u307e\u305a1.5~3%\u306e\u30d2\u30dd\u30af\u30ed\u3060\u304c\u3001\u5316\u5b66\u8005\u3067\u3082\u306a\u3044\u6211\u3005\u304c\u3069\u3046\u3084\u3063\u3066\u305d\u308c\u3092\u5f97\u308d\u3068\u8a00\u3046\u306e\u3060\u308d\u3046\u304b\uff1f<\/p>\n

\u975e\u5e38\u306b\u96e3\u3057\u3044\u3060\u308d\u3046\u3002<\/p>\n

\u4eca\u3067\u3082\u3053\u306e\u624b\u306e\u8a71\u306b\u306a\u308b\u3068\u3001\u30d2\u30dd\u30af\u30ed\u306e\u74f6\u306e\u5f8c\u308d\u306e\u8a18\u8ff0\u3092\u601d\u3044\u51fa\u3059\u3002<\/p>\n

\"\"<\/a><\/p>\n

\"\"<\/a><\/p>\n

\"\"<\/p>\n

\u307e\u305f\u30013%\u30e1\u30d4\u30d0\u30ab\u30a4\u30f3\uff1d3%\u30b9\u30ad\u30e3\u30f3\u30c9\u30cd\u30b9\u30c8\u3092\u4f7f\u7528<\/strong><\/span><\/p>\n

\u3067\u3042\u308b\u304c\u3001\u3053\u308c\u306f\u524d\u6b6f\u306b\u306f\u7121\u7406\u306a\u8a71\u3060\u3002<\/p>\n

5~10\u5206\u3067\u52b9\u679c\u304c\u5207\u308c\u308b\u9ebb\u9154\u3092\u4f7f\u7528\u3057\u3066\u4e0a\u984e\u524d\u6b6f\u306eRegeneration\u3092\u5c0f\u5150\u306b\u30de\u30cd\u30fc\u30b8\u30e1\u30f3\u30c8\u3059\u308b\u3053\u3068\u306f\u4e8b\u5b9f\u4e0a\u3001\u7121\u7406\u3068\u3044\u3063\u3066\u3044\u3044\u3002<\/p>\n

\u3057\u304b\u3082\u3053\u306e\u30b9\u30ad\u30e3\u30f3\u30c9\u30cd\u30b9\u30c8\u4f7f\u7528\u3057\u306a\u3055\u3044\u3001\u3068\u8a00\u3046\u52e7\u544a\u306fCase Report\u3067\u3042\u308b\u3002<\/p>\n

Petrino 2009 Challenges in Regenerative Endodontics: A Case Series<\/strong><\/span><\/a><\/h1>\n

2\u56de\u76ee\u306e\u6cbb\u7642\u306b\u30ad\u30b7\u30ed\u30ab\u30a4\u30f3\u3092\u4f7f\u7528\u3057\u305f\u3089\u3001\u51fa\u8840\u304c\u306a\u304b\u3063\u305f\u306e\u3067\u30b9\u30ad\u30e3\u30f3\u30c9\u30cd\u30b9\u30c8\u3092\u4f7f\u7528\u3057\u307e\u3057\u305f\u3001\u3068\u8a00\u3046\u8ad6\u6587\u306b\u91cd\u3044\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u3042\u308b\u3060\u308d\u3046\u304b\uff1f<\/p>\n

\u79c1\u306b\u306f\u305d\u3046\u306f\u601d\u3048\u306a\u3044\u3002<\/p>\n

\u307e\u305f\u3001\u7b2c3\u306e\u30b4\u30fc\u30eb\u3067\u3042\u308b\u201d\u751f\u6d3b\u53cd\u5fdc\u306e\u7372\u5f97\u201d\u3060\u304c\u79c1\u306f\u3053\u308c\u306f\u8d77\u304d\u306a\u3044\u3068\u601d\u3063\u3066\u3044\u308b\u3002<\/p>\n

\u3042\u304f\u307e\u3067\u3082\u7d4c\u9a13\u7684\u3060\u304c\u2026<\/p>\n

\u3068\u3044\u3046\u3053\u3068\u3067\u4ee5\u4e0a\u306e\u3088\u3046\u306a\u8aac\u660e\u3092\u3057\u3001\u89aa\u5fa1\u3055\u3093\u304c\u6cbb\u7642\u306b\u540c\u610f\u3055\u308c\u305f\u306e\u3067\u6b6f\u79d1\u6cbb\u7642\u304c\u884c\u308f\u308c\u305f\u304c\u2026<\/p>\n

\u5b50\u4f9b\u306f\u53f7\u6ce3\u3067\u3042\u3063\u305f\u3002\u3002\u3002<\/strong><\/span><\/h1>\n

\u305d\u308c\u306f\u305d\u3046\u3060\u3002<\/p>\n

\u8a33\u3082\u308f\u304b\u3089\u305a\u535a\u591a\u306e\u6b6f\u79d1\u533b\u9662\u306b\u9023\u308c\u3066\u884c\u304b\u308c\u3066\u3001<\/p>\n

\u3044\u304d\u306a\u308a\u9ebb\u9154\u3092\u3055\u308c\u3066\uff08\u6b6f\u79d1\u6cbb\u7642\u306a\u3069\u3057\u305f\u3053\u3068\u304c\u306a\u3044\uff09\u3001<\/p>\n

\u30b4\u30e0\u306e\u30b7\u30fc\u30c8\u3092\u4ed8\u3051\u3089\u308c\u3066\u3001<\/p>\n

\u6b6f\u306b\u7a74\u3092\u958b\u3051\u3089\u308c\u3066\u3001<\/p>\n

\u6d17\u6d44\u3055\u305b\u3089\u308c\u3001<\/p>\n

\u6c34\u9178\u5316\u30ab\u30eb\u30b7\u30a6\u30e0\u3092\u8cbc\u85ac\u3055\u308c\u308b\u306e\u3067\u3042\u308b\u3002<\/p>\n

\u79c1\u3082\u6c34\u9178\u5316\u30ab\u30eb\u30b7\u30a6\u30e0\u3092\u4e45\u3005\u306b\u4f7f\u7528\u3057\u305f\u3002<\/strong><\/span><\/h1>\n

\u3053\u306e\u6cbb\u7642\u4ee5\u5916\u306b\u4f7f\u3044\u6240\u304c\u306a\u3044\u304b\u3089\u3060\u3002<\/p>\n

1\u56de\u76ee\u306e\u6cbb\u7642\u304c\u7d42\u308f\u308a\u30012\u56de\u76ee\u306f1\u30f6\u6708\u5f8c\u306b\u4e88\u7d04\u3092\u3068\u3089\u308c\u305f\u3002<\/p>\n

\u305d\u308c\u304c\u3053\u306e\u65e5(2021.12.28)\u3067\u3042\u3063\u305f\u3002<\/p>\n

EDTA 20ml\u3067\u6839\u7ba1\u5185\u3092\u6d17\u6d44\u3059\u308b\u3002<\/p>\n

\"\"<\/p>\n

\u305d\u306e\u610f\u5473\u306f<\/p>\n

EDTA promotes exposure of growth factors in dentin, differentiation of stem cells into
\nodontoblast like cells and adhesion of those cells to dentin.<\/p>\n

\n

EDTA\u306f\u6839\u7ba1\u58c1\u3092\u30a8\u30c3\u30c1\u30f3\u30b0\u3057\u3066Stem cell\u3092\u8c61\u7259\u82bd\u7d30\u80de\u306b\u5206\u5316\u3055\u305b\u308b<\/strong><\/span><\/h1>\n<\/blockquote>\n

\u306e\u3067\u3042\u308b\u3002<\/p>\n

\u305d\u3057\u3066\u3001\u6839\u7ba1\u5185\u3092\u30da\u30fc\u30d1\u30fc\u30dd\u30a4\u30f3\u30c8\u3067\u4e7e\u71e5\u3057<\/p>\n

\"\"<\/p>\n

\u30d5\u30a1\u30a4\u30eb(K#35,#30,#25)\u306e\u5148\u7aef\u3092\u30d9\u30f3\u30c9\u3057\u3066\u6839\u7ba1\u306b\u633f\u5165\u3057\u3001\u6839\u5c16\u3078\u7a81\u304d\u51fa\u3057\u3066\u51fa\u8840\u3092\u4fc3\u3057\u305f\u3002<\/p>\n

\"\"<\/p>\n

\"\"<\/p>\n

\u3053\u306e\u6cbb\u7642\u306e\u30e1\u30a4\u30f3\u30fb\u30a4\u30d9\u30f3\u30c8\u306b\u306a\u308b\u90e8\u5206\u3067\u3042\u308b\u3002<\/p>\n

\u30ad\u30b7\u30ed\u30ab\u30a4\u30f3\u3092\u4f7f\u7528\u3057\u305f\u304c\u2026\u51fa\u8840\u306f\u304d\u3061\u3093\u3068\u8d77\u3053\u3063\u3066\u3044\u308b\u3002<\/p>\n

\"\"<\/p>\n

\u305d\u3057\u3066\u4e45\u3005\u4f7f\u7528\u3057\u305fColla-Plug\u3092\u8840\u9905\u306e\u4e0a\u306b\u7f6e\u3044\u3066\u3001<\/p>\n

\"\"<\/p>\n

\"\"<\/p>\n

\u305d\u306e\u4e0a\u306bBC Putty\u3092\u7f6e\u3044\u3066CR\u5145\u586b\u3057\u3066\u5c01\u9396\u3057\u305f\u3002<\/p>\n

\"\"<\/p>\n

\u6cbb\u7642\u5f8c\u306b\u30c7\u30f3\u30bf\u30eb\u64ae\u5f71\u3092\u304a\u3053\u306a\u3063\u305f\u3002<\/p>\n

\u4ee5\u4e0b\u306b\u306a\u308b\u3002<\/p>\n

\"\"<\/p>\n

\"\"<\/p>\n

\u6b21\u56de\u306f\u534a\u5e74\u5f8c\u306b\u3001\u6b6f\u5185\u7642\u6cd5\u5b66\u7684\u691c\u67fb\u3068PA\u64ae\u5f71\u3067\u3042\u308b\u3002<\/p>\n

\u305d\u3057\u30661\u5e74\u5f8c\u306b\u3001\u6b6f\u5185\u7642\u6cd5\u5b66\u7684\u691c\u67fb\u3001PA\u64ae\u5f71\u3001CBCT\u3067\u3042\u308b\u3002<\/p>\n

\u3055\u3089\u306b1\u5e74\u5f8c\u306b\u3001\u6b6f\u5185\u7642\u6cd5\u5b66\u7684\u691c\u67fb\u3001PA\u64ae\u5f71\u3001CBCT\u3067\u3042\u308b\u3002<\/p>\n

\u3068\u3044\u3046\u3053\u3068\u3067\u3053\u306e\u65e5\u306e\u6cbb\u7642\u304c\u7d42\u4e86\u3057\u305f\u3002<\/p>\n

\u7d4c\u904e\u89b3\u5bdf\u3067\u306f\u3001\u4e0a\u3067\u65e2\u306b\u8a18\u3057\u305f<\/p>\n

\u2460Primary goal: The elimination of symptoms and the evidence of bony healing.\uff08\u7b2c1\u306e\u30b4\u30fc\u30eb\uff1a\u75c7\u72b6\u306e\u55aa\u5931\u3068\u6839\u5c16\u75c5\u5909\u306e\u6cbb\u7652\uff09<\/p>\n

\u2461Secondary goal: Increased root wall thickness and\/or increased root length(desirable, but perhaps not essential)\uff08\u7b2c2\u306e\u30b4\u30fc\u30eb\uff1a\u6839\u7ba1\u58c1\u30fb\u6b6f\u6839\u306e\u6210\u9577\u3002\u7406\u60f3\u7684\u3060\u304c\u30de\u30b9\u30c8\u3067\u306f\u306a\u3044\uff09<\/p>\n

\u2462Tertiary goal: Positive response to vitality testing (which if achieved, could\u00a0indicate a more organized vital pulp tissue)\uff08\u7b2c3\u306e\u30b4\u30fc\u30eb\uff1a\u751f\u6d3b\u53cd\u5fdc\u306e\u7372\u5f97\uff09<\/p>\n

\u306a\u3069\u3092check\u3059\u308b\u3002<\/p>\n

\u9577\u3044\u6226\u3044\uff08\u3068\u8a00\u3063\u3066\u308230\u5206\u3082\u304b\u304b\u3063\u3066\u3044\u306a\u3044\u304c\uff09\u306f\u7d42\u4e86\u3057\u305f\u3002<\/p>\n

\u3053\u306e\u3088\u3046\u306b\u3001<\/p>\n

\u79c1\u306f\uff08\u5f53\u6b6f\u79d1\u533b\u9662\u306f\uff09\u5b50\u4f9b\u306e\u6cbb\u7642\u3082\u884c\u3063\u3066\u3044\u308b\u3002<\/strong><\/span><\/h1>\n

USC\u306e\u6642\u306e\u3001PEDO Time\u3092\u601d\u3044\u51fa\u3059\u3002<\/p>\n

\u6bce\u90311\u56de\u306e\u751f\u8d04\u6642\u9593\u3067\u3042\u3063\u305f\u2026<\/p>\n

\u4eca\u56de\u306e\u5b50\u306f\u6cbb\u7642\u306f\u4e0a\u624b\u3067\u3042\u3063\u305f\u304c\u3001\u9ebb\u9154\u3092\u3059\u308b\u3068\u304b\u3001\u9014\u4e2d\u3067\u75db\u304f\u306a\u308b\u3068\u304b\u305d\u3046\u3044\u3046\u306e\u304cNG\u3067\u9014\u4e2d\u3001\u4f55\u56de\u304b\u53f7\u6ce3\u3057\u3066\u6cbb\u7642\u306e\u5b8c\u4e86\u304c\u5371\u3046\u3044\u3068\u3053\u308d\u3060\u3063\u305f\u3002<\/p>\n

\u3057\u304b\u3057\u307e\u3042\u3053\u308c\u306f\u3001<\/p>\n

1\u56de\u76ee\u306e\u6cbb\u7642\u306fSinus tract\u304c\u3042\u3063\u305f\u3063\u3053\u3068\u304b\u3089\u9ebb\u9154\u304c\u5207\u308c\u3084\u3059\u304f\u6cbb\u7642\u9014\u4e2d\u306b\u75db\u307f\u304c\u51fa\u3084\u3059\u3044\u3068\u3044\u3048\u308b\u304c\u3001<\/p>\n

2\u56de\u76ee\u306fSinus tract\u306f\u6d88\u5931\u3057\u305f\u305f\u3081\u75db\u307f\u306f\u51fa\u306b\u304f\u3044\u3068\u3044\u3048\u308b\u3002<\/p>\n

\u3068\u3044\u3046\u3053\u3068\u3067\u3001\u4eca\u56de\u3082\u3053\u306e\u5b50\u306f\u3088\u304f\u9811\u5f35\u3063\u305f\u3002<\/p>\n

\u3055\u3066\u3001\u7686\u3055\u3093\u306f\u6b21\u56de\u306e\u7d4c\u904e\u89b3\u5bdf\u3092\u304a\u5f85\u3061\u3044\u305f\u3060\u304d\u305f\u3044\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

7\u6b73\u306e\u5973\u5150\u3002 \u30bb\u30df\u30ca\u30fc\u306b\u51fa\u3066\u3044\u308b\u5148\u751f\u304b\u3089\u306e\u7d39\u4ecb\u3067\u770c\u5916\u304b\u3089\u6765\u9662\u3055\u308c\u305f\u3002 \u4e3b\u8a34\u306f\u524d\u6b6f\u90e8\u306e\u4e3b\u5f35\u3068\u5931\u6d3b\u306b\u3068\u3082\u306a\u3046\u6839\u306e\u672a\u9589\u9396\uff08\u7d39\u4ecb\u3055\u308c\u305f\u6b6f\u79d1\u533b\u5e2b\u306e\u4e3b\u8a34\u304b\u3082\u3057\u308c\u306a\u3044\u3002\uff09 \u6b6f\u5185\u7642\u6cd5\u5b66\u7684\u691c\u67fb\u3092\u304a\u3053\u306a\u3063\u305f\u3002 #8 Cold+1\/3, Pe […]<\/p>\n","protected":false},"author":1,"featured_media":5809,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false},"categories":[17,3],"tags":[],"class_list":["post-5804","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-regeneration","category-3"],"yoast_head":"\nRegenerative Endodontics: AAE\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3068\u5b9f\u969b\u306e\u6cbb\u7642\u306e\u76f8\u9055\u2026\u5c0f\u5150\u306e\u6cbb\u7642\u301c#9 Regeneration 2\u56de\u76ee\u7d42\u4e86\u21e8\u7d4c\u904e\u89b3\u5bdf\u3078\u79fb\u884c - \u307e\u3064\u3046\u3089\u6b6f\u79d1\u533b\u9662 \u6b6f\u5185\u7642\u6cd5\u5c02\u9580\u5ba4<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/fukuoka-endodontics.com\/?p=5804\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Regenerative Endodontics: AAE\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3068\u5b9f\u969b\u306e\u6cbb\u7642\u306e\u76f8\u9055\u2026\u5c0f\u5150\u306e\u6cbb\u7642\u301c#9 Regeneration 2\u56de\u76ee\u7d42\u4e86\u21e8\u7d4c\u904e\u89b3\u5bdf\u3078\u79fb\u884c - \u307e\u3064\u3046\u3089\u6b6f\u79d1\u533b\u9662 \u6b6f\u5185\u7642\u6cd5\u5c02\u9580\u5ba4\" \/>\n<meta property=\"og:description\" content=\"7\u6b73\u306e\u5973\u5150\u3002 \u30bb\u30df\u30ca\u30fc\u306b\u51fa\u3066\u3044\u308b\u5148\u751f\u304b\u3089\u306e\u7d39\u4ecb\u3067\u770c\u5916\u304b\u3089\u6765\u9662\u3055\u308c\u305f\u3002 \u4e3b\u8a34\u306f\u524d\u6b6f\u90e8\u306e\u4e3b\u5f35\u3068\u5931\u6d3b\u306b\u3068\u3082\u306a\u3046\u6839\u306e\u672a\u9589\u9396\uff08\u7d39\u4ecb\u3055\u308c\u305f\u6b6f\u79d1\u533b\u5e2b\u306e\u4e3b\u8a34\u304b\u3082\u3057\u308c\u306a\u3044\u3002\uff09 \u6b6f\u5185\u7642\u6cd5\u5b66\u7684\u691c\u67fb\u3092\u304a\u3053\u306a\u3063\u305f\u3002 #8 Cold+1\/3, Pe […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/fukuoka-endodontics.com\/?p=5804\" \/>\n<meta property=\"og:site_name\" content=\"\u307e\u3064\u3046\u3089\u6b6f\u79d1\u533b\u9662 \u6b6f\u5185\u7642\u6cd5\u5c02\u9580\u5ba4\" \/>\n<meta property=\"article:published_time\" content=\"2021-12-29T17:02:26+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2021-12-30T01:03:31+00:00\" \/>\n<meta property=\"og:image\" 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